Description

2'-Deoxy-2'-Fluoro-N3-[(Pyridin-4-Yl)Methyl]-β-D-Arabinouridine is a high-purity, modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate and building block in the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral and anticancer drugs, particularly those targeting RNA-based mechanisms.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Antiviral Drug Research: Used in R&D for potential therapeutics against RNA viruses, leveraging its modified sugar moiety to inhibit viral replication.
• Oncology Research: Investigated as a component in the development of targeted cancer therapies, including antibody-drug conjugates (ADCs).
• Biochemical Tool: Serves as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and related pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Pre-clinical Development: Used in the synthesis of compounds for pharmacokinetic, pharmacodynamic, and toxicology studies.

Basic Information

Product Name	2'-Deoxy-2'-Fluoro-N3-[(Pyridin-4-Yl)Methyl]-β-D-Arabinouridine
CAS No.	2072145-47-0
Molecular Formula	C16H18FN3O5
Molecular Weight	351.33 g/mol
Synonyms	2'-Deoxy-2'-fluoro-N3-(4-pyridinylmethyl)-β-D-arabinouridine; 2'-F-N3-(4-Pyridylmethyl)-β-D-arabinouridine; 2'-Fluoro-2'-deoxy-N3-(pyridin-4-ylmethyl)arabinouridine; 4-(((2R,3S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-fluoro-2-(hydroxymethyl)tetrahydrofuran-2-yl)methoxy)methyl)pyridine; N3-(Pyridin-4-ylmethyl)-2'-deoxy-2'-fluoro-β-D-arabinouridine; CAS 2072145-47-0
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluoro-N3-[(Pyridin-4-Yl)Methyl]-β-D-Arabinouridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pre-clinical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.