Description

6-Methoxy-9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-9H-Purine is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, where its modified sugar moiety can enhance metabolic stability and target specificity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of next-generation therapeutics, particularly for targeting viral polymerases and specific cellular enzymes.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of nucleoside-based antiviral drugs.
• Antiviral Research: Used in biochemical studies targeting RNA-dependent RNA polymerases (RdRp) of various viruses.
• Oncology Drug Discovery: Serves as a scaffold for creating purine analogs that inhibit cancer cell proliferation.
• Biochemical Probe: Employed in enzymatic assays to study the mechanism of action of nucleoside-processing enzymes.
• Process Chemistry: Utilized in scale-up synthesis for the production of active pharmaceutical ingredients (APIs).
• Academic Research: Fundamental studies in medicinal chemistry exploring structure-activity relationships (SAR) of modified nucleosides.

Basic Information

Product Name	6-Methoxy-9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-9H-Purine
CAS No.	2072145-35-6
Molecular Formula	C11H13FN4O4
Molecular Weight	284.24 g/mol
Synonyms	3'-Deoxy-3'-fluoro-6-methoxy-9-β-D-ribofuranosylpurine; 6-Methoxy-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)purine; 3'-Fluoro-6-methoxy purine nucleoside; 9-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methoxypurine; 6-Methoxy-3'-fluoro-purine riboside; Fluorinated 6-methoxypurine nucleoside
EINECS	Contact for details

Quality Control

Our 6-Methoxy-9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-9H-Purine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.