Description

3-(Methoxycarbonyl)-1-β-D-Ribofuranosyl-Pyridinium is a specialized nucleoside derivative and a key synthetic intermediate in modern pharmaceutical chemistry. This compound matters for its role in the synthesis of novel therapeutic agents, particularly in the development of nucleotide analogs and prodrugs. It is primarily needed by research institutions and pharmaceutical companies engaged in antiviral drug discovery, oncology research, and the development of advanced RNA-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of nucleotide analogs and modified nucleosides used in drug development.
• Antiviral Research: Used in the research and development of prodrugs targeting viral polymerases for diseases such as hepatitis and influenza.
• Oncology Therapeutics: Serves as a precursor in the creation of chemotherapeutic agents that interfere with cancer cell DNA/RNA synthesis.
• Biochemical Research: Employed as a substrate or intermediate in enzymatic studies and metabolic pathway investigations.
• Prodrug Synthesis: Utilized to create masked phosphate prodrugs (e.g., ProTide technology) to enhance drug delivery and bioavailability.
• RNA-Based Therapy Development: A component in the synthesis of modified mRNA and other oligonucleotides for therapeutic applications.

Basic Information

Product Name	3-(Methoxycarbonyl)-1-β-D-Ribofuranosyl-Pyridinium
CAS No.	2064247-61-4
Molecular Formula	C12H15NO7
Molecular Weight	285.25 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-3-(methoxycarbonyl)pyridinium; 3-Carbomethoxy-1-β-D-ribofuranosylpyridinium; 3-Methoxycarbonyl-1-β-D-ribofuranosylpyridinium; Nicotinic acid β-D-ribofuranoside derivative; Pyridinium, 3-(methoxycarbonyl)-1-β-D-ribofuranosyl-; Nucleoside mimetic intermediate; ProTide intermediate precursor
EINECS	Contact for details

Quality Control

Our 3-(Methoxycarbonyl)-1-β-D-Ribofuranosyl-Pyridinium is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.