Description

Bromo-Peg6-Azide is a heterobifunctional polyethylene glycol (PEG) crosslinker featuring a bromoalkyl group and a terminal azide. This compound is essential for creating stable, well-defined bioconjugates and materials via copper-free click chemistry, particularly strain-promoted azide-alkyne cycloaddition (SPAAC). It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors for applications such as antibody-drug conjugate (ADC) development, surface functionalization, and hydrogel synthesis.

Application

• Bioconjugation and ADC Development: Used as a linker to attach cytotoxic payloads or probes to antibodies, proteins, or peptides.
• Surface Modification: Functionalizes nanoparticles, biosensors, and diagnostic arrays for enhanced targeting and detection.
• Polymer and Hydrogel Synthesis: Serves as a crosslinking agent to create PEG-based networks with tailored properties for drug delivery and tissue engineering.
• Chemical Biology Probes: Enables the labeling and tracking of biomolecules in live-cell imaging and proteomics studies.
• Materials Science: Incorporates functional groups into polymers and coatings to modify surface characteristics and reactivity.
• Diagnostic Reagent Formulation: Used in the development of assay components and diagnostic kits requiring stable, water-soluble linkers.

Basic Information

Product Name	Bromo-Peg6-Azide
CAS No.	2062663-64-1
Molecular Formula	C19H36BrN3O7
Molecular Weight	498.41 g/mol
Synonyms	1-Bromo-2-(2-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethane; Bromo-PEG6-N3; Br-PEG6-Azide; 2-(2-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl Bromide; Azido-PEG6-Bromide; N3-PEG6-Br; Bromohexaethylene glycol azide; PEG6 Bromo Azide
EINECS	Contact for details

Quality Control

Our Bromo-Peg6-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in water, DMSO, DMF, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.