Description

Gdc-0077 is a high-purity, small-molecule chemical compound identified by CAS No. 2060571-02-8. This compound is a critical intermediate or active pharmaceutical ingredient (API) in advanced research and therapeutic development, valued for its precise biological activity. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in oncology and targeted drug discovery programs.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key intermediate or reference standard in the synthesis and optimization of novel therapeutic agents.
• Oncology Drug Discovery: Used in preclinical studies targeting specific kinase pathways for the development of new cancer treatments.
• Biochemical Assays: Employed as a potent and selective inhibitor in high-throughput screening (HTS) and mechanism-of-action studies.
• Reference Standard: Provides a certified material for analytical method development, validation, and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs for fundamental studies in cell signaling and molecular biology.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials.

Basic Information

Product Name	Gdc-0077
CAS No.	2060571-02-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GDC-0077; GDC0077; 2060571-02-8; Inavolisib; RG-6114; RG6114; (S)-2-(1-(4-(4-(Dimethylamino)piperidine-1-carbonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-5-methyl-3-phenyl-3,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; PI3Kα inhibitor
EINECS	Contact for details

Quality Control

Every batch of Gdc-0077 (CAS 2060571-02-8) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity	≤0.5%
Total Impurities	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.