Description

1-((2S,3R,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)-3-Methyltetrahydrofuran-2-Yl)Pyrimidine-2,4(1H,3H)-Dione is a high-purity fluorinated nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel antiviral and anticancer therapeutics, particularly those targeting viral polymerases and cellular DNA/RNA pathways. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation nucleoside analog drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel antiviral agents, including potential treatments for hepatitis and other viral infections.
• Anticancer Drug Research: Used in the synthesis of experimental nucleoside analogs designed to inhibit tumor cell proliferation.
• Biochemical Research: Serves as a modified nucleoside substrate in enzymatic studies and for probing nucleic acid interactions.
• Prodrug Development: Employed in the design and synthesis of prodrugs to enhance the bioavailability and targeting of active pharmaceutical ingredients.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing routes of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-((2S,3R,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)-3-Methyltetrahydrofuran-2-Yl)Pyrimidine-2,4(1H,3H)-Dione
CAS No.	2041584-99-8
Molecular Formula	C10H13FN2O5
Molecular Weight	260.22 g/mol
Synonyms	3'-Fluoro-3'-methyl-2'-deoxyuridine; 3'-Fluoro-3'-methyl-dU; 1-[(2S,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione; Fluorinated 3'-methyl-dU derivative; 3'-F-3'-Me-dU; 2'-Deoxy-3'-fluoro-3'-methyluridine
EINECS	Contact for details

Quality Control

Every batch of our 1-((2S,3R,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)-3-Methyltetrahydrofuran-2-Yl)Pyrimidine-2,4(1H,3H)-Dione is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research. Our quality protocols are designed to support GMP-grade applications and regulatory filings. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.