Description

m-Peg4-(Ch2)8-Phosphonic Acid is a specialized bifunctional linker molecule featuring a phosphonic acid head group and a tetraethylene glycol (PEG4) spacer. This compound matters for its unique ability to provide stable surface anchoring via the phosphonate moiety while offering excellent aqueous solubility and biocompatibility through the hydrophilic PEG chain. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors for creating functionalized surfaces, targeted drug delivery systems, and advanced polymer conjugates.

Application

• Surface Functionalization: Used to create self-assembled monolayers (SAMs) on metal oxide surfaces (e.g., titanium, stainless steel) for biosensor and implant coating applications.
• Bioconjugation & Drug Delivery: Serves as a versatile linker for attaching therapeutic agents, peptides, or targeting ligands to nanoparticles or other carriers, leveraging the PEG spacer for enhanced solubility and reduced immunogenicity.
• Polymer Chemistry: Acts as a functional initiator or chain-transfer agent in controlled radical polymerization to synthesize phosphonate-terminated polymers for dispersants or scale inhibitors.
• Chelation & Metal Binding: Utilized in analytical chemistry and water treatment processes due to the strong chelating properties of the phosphonic acid group for metal ions.
• Nanomaterial Synthesis: Employed as a stabilizing agent or surface modifier in the synthesis of quantum dots, magnetic nanoparticles, and other inorganic nanomaterials to improve colloidal stability in aqueous media.
• Diagnostic Assays: Facilitates the immobilization of biomolecules (antibodies, DNA) on assay platforms for improved detection sensitivity and specificity.

Basic Information

Product Name	m-Peg4-(Ch2)8-Phosphonic Acid
CAS No.	2028281-85-6
Molecular Formula	C18H39O9P
Molecular Weight	454.47 g/mol
Synonyms	8-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]octylphosphonic Acid; (8-{2-[2-(2-Methoxy-ethoxy)-ethoxy]-ethoxy}-octyl)-phosphonic Acid; mPEG4-C8-Phosphonic Acid; Tetraethylene glycol monomethyl ether C8-phosphonate; O-Methyl-octa(ethylene glycol)-ω-phosphonic acid; Phosphonic acid, P-[8-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]octyl]-; HO-PEG4-C8-Phosphonate
EINECS	Contact for details

Quality Control

Our m-Peg4-(Ch2)8-Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure compliance with precise specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Phosphonic Acid Content (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.