Description

3-Bromo-2,4,5,6-Tetrafluorobenzylalcohol is a high-value, multi-fluorinated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates where it can modulate lipophilicity, metabolic stability, and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, contributing to improved charge transport and thermal stability in display technologies.
• Polymer & Resin Modifier: Incorporated as a functional monomer to introduce fluorine and bromine functionalities into specialty polymers, enhancing flame retardancy and chemical resistance.
• Cross-Coupling Reactions: The bromine atom provides a handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling rapid diversification of molecular scaffolds.
• Ligand & Catalyst Development: Utilized in the synthesis of novel fluorinated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-2,4,5,6-Tetrafluorobenzylalcohol
CAS No.	292621-48-8
Molecular Formula	C7H3BrF4O
Molecular Weight	259.00 g/mol
Synonyms	(3-Bromo-2,4,5,6-tetrafluorophenyl)methanol; 2,4,5,6-Tetrafluoro-3-bromobenzyl Alcohol; 3-Bromo-2,4,5,6-tetrafluorobenzenemethanol; α-Hydroxymethyl-3-bromo-2,4,5,6-tetrafluorotoluene; Benzyl alcohol, 3-bromo-2,4,5,6-tetrafluoro-; 3-Bromo-2,4,5,6-tetrafluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2,4,5,6-Tetrafluorobenzylalcohol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/GC), identity (IR, NMR), and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and sources of fluoride ions. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.