Description

Bicyclo[2.2.1]Heptane-1-Carbonyl Fluoride, 7,7-Dimethyl-2-Oxo-, (1S,4R)- (9Ci) is a high-purity, stereochemically defined fluorinated building block of significant interest in advanced organic synthesis. Its unique bicyclic norbornane skeleton, combined with the reactive carbonyl fluoride and ketone functionalities, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its rigid structure can contribute to biological activity and environmental stability.
• Fluorination Chemistry: Serves as a versatile fluorinating agent or a source of fluorinated motifs in organofluorine chemistry, enabling the introduction of fluorine atoms into target molecules.
• Material Science Research: Employed in the synthesis of specialty polymers, resins, or liquid crystals where the norbornane core can impart desirable thermal and mechanical properties.
• Catalyst & Ligand Development: Acts as a precursor for creating novel chiral ligands and catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A critical tool for methodological development in organic synthesis, particularly in studies involving ring-strained systems and stereoselective transformations.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-1-Carbonyl Fluoride, 7,7-Dimethyl-2-Oxo-, (1S,4R)- (9Ci)
CAS No.	289722-43-6
Molecular Formula	C10H13FO2
Molecular Weight	184.21 g/mol
Synonyms	(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-carbonyl fluoride; (1S,4R)-1-(Fluorocarbonyl)-7,7-dimethyl-2-norbornanone; endo-7,7-Dimethyl-2-oxonorbornane-1-carbonyl fluoride; 1-Carboxyfluoride-7,7-dimethyl-2-norbornanone, (1S,4R)-; 289722-43-6; Bicyclo[2.2.1]heptane-1-carbonyl fluoride, 7,7-dimethyl-2-oxo-, (1S,4R)-
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-1-Carbonyl Fluoride, 7,7-Dimethyl-2-Oxo-, (1S,4R)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.