Description

Amorolfine is a potent allylamine antifungal agent widely recognized for its efficacy against dermatophytes, yeasts, and molds. Its primary commercial value lies in its use as the active pharmaceutical ingredient (API) in topical formulations for treating fungal infections. This compound is essential for pharmaceutical manufacturers developing antifungal creams, lacquers, and solutions. Amorolfine CAS NO 288583-04-0 is critical for producing high-quality, reliable antifungal medications.

Application

• Active Pharmaceutical Ingredient (API) in topical antifungal creams and ointments.
• Key component in medicated nail lacquers for the treatment of onychomycosis.
• Formulation base for antifungal powders and sprays for dermatological use.
• Raw material in veterinary pharmaceuticals for treating fungal infections in animals.
• Reference standard in analytical laboratories for quality control and research.
• Intermediate in the synthesis of more complex antifungal drug compounds.
• Biochemical research tool for studying ergosterol biosynthesis inhibition.

Basic Information

Product Name	Amorolfine
CAS No.	288583-04-0
Molecular Formula	C21H35NO
Molecular Weight	317.51 g/mol
Synonyms	Amorolfine Hydrochloride; (R,S)-2,6-Dimethyl-4-[2-methyl-3-(p-tert-butylphenyl)propyl]morpholine; Ro 14-4767/000; Loceryl (trade name); (RS)-2,6-Dimethyl-4-[2-methyl-3-(4-tert-butylphenyl)propyl]morpholine; (±)-Amorolfine
EINECS	Contact for details

Quality Control

Our Amorolfine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee supply reliability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Water (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.