Description

6-Bromo-2-Chloroquinoline-4-Carbonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its value lies in its reactive carbonyl chloride and halogenated quinoline structure, enabling precise derivatization for creating complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialized materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used to develop advanced herbicides, fungicides, and pesticides by serving as a core scaffold for bioactive molecules.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for light-emitting diodes (OLEDs).
• Chemical Biology: Acts as a versatile probe or linker for bioconjugation and the development of chemical tools for biological target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and complex intermediates on a commercial scale.

Basic Information

Product Name	6-Bromo-2-Chloroquinoline-4-Carbonyl Chloride
CAS No.	287176-63-0
Molecular Formula	C11H4BrCl2NO
Molecular Weight	324.97 g/mol
Synonyms	6-Bromo-2-chloroquinoline-4-carbonyl chloride; 6-Bromo-2-chloro-4-quinolinecarbonyl chloride; 2-Chloro-6-bromoquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-bromo-2-chloro-; 287176-63-0; Quinoline-4-carbonyl chloride, 6-bromo-2-chloro-; 6-Bromo-2-chloroquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2-Chloroquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.