Description

Chloroacetyl Chloride-13C2 is a stable isotope-labeled derivative of chloroacetyl chloride, where two carbon atoms are replaced with the 13C isotope. This compound is essential for creating isotopically labeled compounds used as internal standards in quantitative mass spectrometry, ensuring unparalleled analytical accuracy and traceability. It is a critical reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise metabolic and pharmacokinetic studies.

Application

• Internal Standard Synthesis: Primary use as a precursor for synthesizing carbon-13 labeled internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Pharmaceutical Research: Enables the development of isotopically labeled drug candidates and metabolites for advanced Absorption, Distribution, Metabolism, and Excretion (ADME) studies.
• Agrochemical Analysis: Used in the production of labeled pesticide metabolites for environmental fate studies and residue analysis to meet stringent regulatory requirements.
• Biochemical Tracing: Facilitates the creation of probes for metabolic pathway tracing and proteomics research, providing insights into biological mechanisms.
• Chemical Reference Materials: Serves as a key building block for certified reference materials (CRMs) to ensure quality control and method validation in analytical laboratories.

Basic Information

Product Name	Chloroacetyl Chloride-13C2
CAS No.	286367-76-8
Molecular Formula	13C2Cl2HO
Molecular Weight	~115.92 g/mol
Synonyms	2-Chloroacetyl-13C2 chloride; Chloroacetic-13C2 acid chloride; Monochloroacetyl-13C2 chloride; 13C2-Chloroacetyl chloride; Carbon-13 labeled chloroacetyl chloride; Isotopic chloroacetyl chloride; [13C2]-Chloroacetyl chloride
EINECS	Contact for details

Quality Control

Our Chloroacetyl Chloride-13C2 is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom% 13C), chemical purity, and identity confirmation. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee batch-to-batch consistency and reliability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat and ignition sources. Due to its nature as a strong acid/organic solvent and highly volatile compound, it should be handled in a fume hood and kept separate from bases, amines, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (13C)	≥99 atom%
Chemical Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.