Description

(Trimethylsilyl)Acetylene-13C2 is a stable, isotopically labeled derivative of trimethylsilylacetylene, where both carbon atoms in the acetylene unit are the carbon-13 isotope. This compound is a critical building block for introducing a labeled acetylene moiety into complex molecules for advanced research and analytical applications. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications requiring isotopic tracing, such as metabolic studies, reaction mechanism elucidation, and the development of labeled active pharmaceutical ingredients (APIs).

Application

• Synthesis of Carbon-13 Labeled Compounds: A key precursor for incorporating stable isotopic labels into target molecules for Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS) studies.
• Pharmaceutical Research & Development: Used in the synthesis of isotopically labeled drug candidates for pharmacokinetic, pharmacodynamic, and metabolic pathway tracing studies.
• Mechanistic Organic Chemistry: Employed as a tracer to study reaction mechanisms, intermediates, and catalytic cycles in academic and industrial research settings.
• Agrochemical Development: Facilitates the creation of labeled pesticides or herbicides to study environmental fate, degradation pathways, and metabolic products in plants.
• Material Science: Serves as a monomer or building block for synthesizing novel polymers, dendrimers, or advanced materials with specific isotopic compositions for specialized properties.
• Diagnostic Agent Synthesis: Potential use in the development of contrast agents or probes for medical imaging techniques like MRI, where carbon-13 labeling is advantageous.

Basic Information

Product Name	(Trimethylsilyl)Acetylene-13C2
CAS No.	285138-86-5
Molecular Formula	C132H8Si or (CH3)3SiC≡13C13CH
Molecular Weight	100.20 g/mol (for 13C2 labeled form)
Synonyms	Trimethyl(13C2ethynyl)silane; (13C2)Trimethylsilylacetylene; TMSA-13C2; Ethynyltrimethylsilane-13C2; 1-Trimethylsilyl-1,2-13C2-acetylene; (Trimethylsilyl)ethyne-13C2; TMS-acetylene-13C2
EINECS	Contact for details

Quality Control

Our (Trimethylsilyl)Acetylene-13C2 is produced under strict quality management protocols to ensure the highest isotopic and chemical purity for sensitive research applications. Each batch is characterized using advanced analytical techniques including NMR, GC-MS, and IR spectroscopy to confirm identity, isotopic enrichment (typically >99 atom % 13C), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress and pressure changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
13C Isotopic Enrichment	≥ 99 atom %
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.