Description

Sorafenib is a potent, small-molecule multi-kinase inhibitor that plays a critical role in targeted cancer therapy. This compound is essential for pharmaceutical research and development, offering a mechanism to inhibit tumor cell proliferation and angiogenesis. It is primarily utilized by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in oncology drug development and production.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of targeted cancer therapeutics.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research for studying kinase signaling pathways and mechanisms of action in oncology.
• Preclinical Development for efficacy and pharmacokinetic studies in animal models.
• Process Development for scaling up synthesis and optimizing manufacturing routes.
• Generic Drug Manufacturing for the production of bioequivalent versions of approved sorafenib-based medications.

Basic Information

Product Name	Sorafenib
CAS No.	284461-73-0
Molecular Formula	C21H16ClF3N4O3
Molecular Weight	464.82 g/mol
Synonyms	Sorafenib Tosylate; BAY 43-9006; Nexavar; 4-[4-[[4-Chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide; Sorafenib free base; BAY 54-9085; Sorafenib (BAY 43-9006)
EINECS	Contact for details

Quality Control

Our Sorafenib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting high standards for pharmaceutical intermediates and APIs. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.