Description

Denibulin is a potent and selective small molecule inhibitor with significant research and development interest. This compound is valued for its targeted mechanism of action, which makes it a crucial tool in advanced pharmaceutical and life science applications. It is primarily utilized by researchers and developers in the fields of oncology and medicinal chemistry for drug discovery and preclinical studies.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutic agents.
• Oncology Studies: Investigation into its mechanism as a tubulin polymerization inhibitor for potential anti-cancer applications.
• Biochemical Assays: Used as a reference standard or pharmacological probe in high-throughput screening and target validation.
• Medicinal Chemistry: Serving as a core scaffold for structure-activity relationship (SAR) studies and analog synthesis.
• Academic Research: Fundamental research in cell biology and signal transduction pathways at universities and institutes.

Basic Information

Product Name	Denibulin
CAS No.	284019-34-7
Molecular Formula	C₁₉H₂₁N₃O₅S
Molecular Weight	403.45 g/mol
Synonyms	MN-029; (S)-N-(3-Chloro-4-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine; Denibulin hydrochloride; Tosedostat; Benzamide, N-[3-chloro-4-fluorophenyl]-6-methoxy-7-[[(1-methyl-4-piperidinyl)methoxy]methoxy]-4-quinazolinamine; UNII-6Q5H5I16Q5
EINECS	Contact for details

Quality Control

Our Denibulin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.