Description

2',5'-Dideoxy-8,5'-Cycloadenosine is a chemically modified nucleoside analog, representing a valuable building block and research compound in advanced organic synthesis. Its unique bridged structure makes it a critical intermediate for developing novel pharmaceutical agents and biochemical probes. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and nucleotide-based therapeutic development.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate adenosine receptor pathways and nucleotide metabolism.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Probe Development: Utilized in the synthesis of labeled compounds (e.g., fluorescent or radioactive) for diagnostic and mechanistic studies.
• Academic Research: Employed in universities and research institutes for fundamental studies in organic chemistry and nucleoside chemistry.

Basic Information

Product Name	2',5'-Dideoxy-8,5'-Cycloadenosine
CAS No.	275821-04-0
Molecular Formula	C12H13N5O2
Molecular Weight	259.27 g/mol
Synonyms	8,5'-Cyclo-2',5'-dideoxyadenosine; 2',5'-Dideoxy-8,5'-cycloadenosine; 8,5'-Anhydro-2',5'-dideoxyadenosine; 2',5'-Dideoxy-8,5'-ethanoadenosine; 8,5'-Cycloadenosine, 2',5'-dideoxy-; Adenosine, 2',5'-dideoxy-8,5'-cyclo-
EINECS	Contact for details

Quality Control

Our 2',5'-Dideoxy-8,5'-Cycloadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.