Description

2-Amino-9-(2-o-Methyl-β-D-Ribofuranosyl)Purine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial building block for the synthesis of novel antiviral and anticancer agents, where structural modifications are key to enhancing efficacy and selectivity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and prodrug development. The material is supplied with a high level of purity and consistency to meet the stringent requirements of modern drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies investigating enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Prodrug Synthesis: Serves as a core structure for designing prodrugs aimed at improving bioavailability and targeted delivery.
• Antiviral Agent Development: Research into compounds active against a range of DNA and RNA viruses.
• Labeled Compound Synthesis: Potential starting material for the preparation of isotopically labeled compounds for metabolic and pharmacokinetic studies.
• Academic Research: Employed in university and institutional labs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	2-Amino-9-(2-o-Methyl-β-D-Ribofuranosyl)Purine
CAS No.	274259-35-7
Molecular Formula	C11H15N5O4
Molecular Weight	281.27 g/mol
Synonyms	2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine; 2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purine; 2-Aminopurine riboside 2'-O-methyl ether; 2'-O-Methyl-2-aminoadenosine; 9-(2-O-Methyl-β-D-ribofuranosyl)-2-aminopurine; 2-Amino-2'-O-methyladenosine; 2'-O-Methylisoguanosine; Modified Nucleoside 274259-35-7
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-9-(2-o-Methyl-β-D-Ribofuranosyl)Purine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to support cGMP compliance for use as a pharmaceutical intermediate. Standard testing includes HPLC for assay and purity, along with specific identification tests. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.