Description

[1,1'-Binaphthalene]-2,2'-Diol, (1S)-, Compd. With 5-Methoxy-2-[(S)-[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)Methyl]Sulfinyl]-1H-Benzimidazole (1:1) is a high-purity, non-racemic chiral compound formed as a 1:1 molecular complex. This material is of significant value as a chiral resolving agent or intermediate in advanced organic synthesis, particularly for the separation of enantiomers. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing optically pure active pharmaceutical ingredients (APIs).

Application

• Chiral Resolution Agent: For the separation of racemic mixtures in pharmaceutical intermediate synthesis.
• Asymmetric Synthesis Intermediate: Used in the preparation of enantiomerically pure compounds for drug discovery.
• Pharmaceutical Reference Standard: Serves as a high-purity standard for analytical method development and quality control.
• Catalyst Ligand Precursor: Potential use in the development of chiral catalysts for stereoselective reactions.
• Academic and Industrial Research: A key reagent for studying chiral recognition and separation mechanisms.
• Process Development: Employed in scaling up synthetic routes for chiral drugs in pilot plants.

Basic Information

Product Name	[1,1'-Binaphthalene]-2,2'-Diol, (1S)-, Compd. With 5-Methoxy-2-[(S)-[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)Methyl]Sulfinyl]-1H-Benzimidazole (1:1)
CAS No.	272776-12-2
Molecular Formula	C41H38N2O6S
Molecular Weight	686.82 g/mol
Synonyms	(S)-BINOL Compd. with (S)-Omeprazole (1:1); (S)-1,1'-Bi-2-naphthol Compd. with (S)-Omeprazole; (S)-BINOL-(S)-Omeprazole Complex; (S)-Omeprazole-(S)-BINOL Salt; 5-Methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-benzimidazole compound with (1S)-1,1'-binaphthalene-2,2'-diol (1:1); (S)-Omeprazole (S)-BINOLate; Chiral Omeprazole-BINOL Complex
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.