Description

4-Pyrimidinecarbonyl Chloride, 6-Chloro- (9Ci) is a high-purity, reactive heterocyclic building block essential for advanced organic synthesis. Its core value lies in its dual functionality, serving as a key precursor for constructing complex pyrimidine-based scaffolds found in pharmaceuticals and agrochemicals. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific pyrimidine motifs for activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, bioconjugation, or as a core structure in probe molecule design.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	4-Pyrimidinecarbonyl Chloride, 6-Chloro- (9Ci)
CAS No.	263270-52-6
Molecular Formula	C5H2Cl2N2O
Molecular Weight	176.99 g/mol
Synonyms	6-Chloro-4-pyrimidinecarbonyl chloride; 6-Chloropyrimidine-4-carbonyl chloride; 4-Pyrimidinecarbonyl chloride, 6-chloro-; 6-Chloro-4-pyrimidine carboxylic acid chloride; 6-Chloropyrimidine-4-carboxylic acid chloride; 6-Chloro-4-carboxypyrimidine chloride; 263270-52-6
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinecarbonyl Chloride, 6-Chloro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.