Description

2-Methyl-5-(Trifluoromethyl)Benzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 2-methyl-5-(trifluoromethyl)benzoyl moiety. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients, intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl-substituted aromatic system for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides where the trifluoromethyl group contributes to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced functional materials, including liquid crystal compounds and organic light-emitting diode (OLED) materials, leveraging its aromatic and electron-withdrawing properties.
• Polymer Chemistry: Employed as a monomer or modifying agent in the production of specialty polymers, such as polyamides or polyesters, to impart specific thermal or chemical resistance.
• Peptide Coupling Reagent: Functions as a coupling agent in peptide synthesis to activate carboxylic acids for amide bond formation.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Benzoyl Chloride
CAS No.	261952-08-3
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	2-Methyl-5-(trifluoromethyl)benzoyl chloride; 5-(Trifluoromethyl)-o-toluoyl chloride; 2-Methyl-alpha,alpha,α-trifluoro-m-toluoyl chloride; m-Toluoyl chloride, 2-methyl-5-(trifluoromethyl)-; 2-Methyl-5-trifluoromethylbenzoyl chloride; Benzoyl chloride, 2-methyl-5-(trifluoromethyl)-; 2-Methyl-5-(trifluoromethyl)benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.