Description

2,6-Difluoro-3-Methylbenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 2,6-difluoro-3-methylbenzoyl moiety. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities. Its specific substitution pattern offers unique steric and electronic properties for targeted molecular design.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a difluorinated benzoyl group.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Polymer Chemistry: Can be employed as a monomer or modifier in the production of specialty polymers with specific thermal or chemical resistance properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.
• Dye and Pigment Intermediate: Used in the synthesis of complex organic dyes and pigments, where fluorine substitution can alter color and lightfastness.

Basic Information

Product Name	2,6-Difluoro-3-Methylbenzoyl Chloride
CAS No.	261763-39-7
Molecular Formula	C9H5ClF2O
Molecular Weight	202.58 g/mol
Synonyms	3-Methyl-2,6-difluorobenzoyl chloride; 2,6-Difluoro-3-methylbenzoic acid chloride; 2,6-Difluoro-m-toluoyl chloride; Benzoyl chloride, 2,6-difluoro-3-methyl-; 261763-39-7; 3-Methyl-2,6-difluorobenzoic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-3-Methylbenzoyl Chloride is manufactured and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support cGMP standards for pharmaceutical applications and can provide documentation to meet regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.