Description

2-Chloro-3-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides valuable electronic and steric properties for modulating the activity of target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronics: Building block for electron-transport materials and charge-modifying units in organic light-emitting diodes (OLEDs) and semiconductors.
• Complex Ligand Synthesis: Intermediate for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRO/CMO) for producing bespoke fluorinated compounds for various R&D applications.

Basic Information

Product Name	2-Chloro-3-(Trifluoromethyl)Benzyl Alcohol
CAS No.	261763-20-6
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	(2-Chloro-3-(trifluoromethyl)phenyl)methanol; 1-(Chloro)-2-(hydroxymethyl)-6-(trifluoromethyl)benzene; α-Hydroxy-2-chloro-α,α,α-trifluoro-m-xylene; 2-Chloro-α,α,α-trifluoro-m-toluyl alcohol; Benzyl alcohol, 2-chloro-3-(trifluoromethyl)-; 2-Chloro-3-trifluoromethylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.