Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzoyl Chloride is a highly reactive and versatile aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen and trifluoromethyl substituents, which enable precise functionalization for creating complex molecules with tailored properties. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce key pharmacophores and structural motifs into active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing benzamide or aryl ketone scaffolds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and halogenated aromatic system.
• Liquid Crystal & OLED Material Production: Used in the creation of advanced electronic materials and fluorinated liquid crystals for displays.
• Polymer Chemistry: Monomer or modifier for synthesizing specialty polymers with enhanced chemical resistance and stability.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions to form amides, esters, and ketones.
• Chemical Research & Development: A valuable tool for medicinal chemistry and material science research to explore new chemical entities.

Basic Information

Item	Details
Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzoyl Chloride
CAS No.	261763-03-5
Molecular Formula	C8H2Cl2F4O
Molecular Weight	261.00 g/mol
Synonyms	3-Chloro-2-fluoro-5-(trifluoromethyl)benzoyl chloride; 2-Fluoro-3-chloro-5-(trifluoromethyl)benzoyl chloride; 5-(Trifluoromethyl)-3-chloro-2-fluorobenzoyl chloride; Benzoyl chloride, 3-chloro-2-fluoro-5-(trifluoromethyl)-; 3-Chloro-2-fluoro-alpha,alpha,α-trifluoro-p-toluoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.