Description

2-Chloro-3,6-Difluorobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the 2-chloro-3,6-difluorobenzoyl moiety, a key structural motif for modulating the biological activity and physical properties of target molecules. This intermediate is essential for research and production in the pharmaceutical and agrochemical industries, particularly for developing active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the difluoro and chloro substituents contribute to improved lipophilicity and binding affinity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers, including polyamides and polyesters, to impart specific chemical resistance or thermal properties.
• Organic Electronic Materials: Intermediate in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	2-Chloro-3,6-Difluorobenzoyl Chloride
CAS No.	261762-42-9
Molecular Formula	C7H2Cl2F2O
Molecular Weight	210.99 g/mol
Synonyms	2-Chloro-3,6-difluorobenzoyl chloride; 3,6-Difluoro-2-chlorobenzoyl chloride; Benzoyl chloride, 2-chloro-3,6-difluoro-; 2-Chloro-3,6-difluorobenzoic acid chloride; 261762-42-9; 2-Chloro-3,6-difluoro-benzoic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3,6-Difluorobenzoyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including GC, HPLC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications and results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.