Description

3-Chloro-2-Fluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on the benzyl alcohol core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a monomer or modifier to introduce fluorine into polymer chains, improving chemical resistance and surface properties.
• Chemical Research & Development: Essential reagent for method development, catalysis studies, and exploring new reaction pathways in organofluorine chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex dyes, flavors, and fragrances requiring specific halogenated motifs.

Basic Information

Product Name	3-Chloro-2-Fluorobenzyl Alcohol
CAS No.	261723-30-2
Molecular Formula	C7H6ClFO
Molecular Weight	160.57 g/mol
Synonyms	(3-Chloro-2-fluorophenyl)methanol; 2-Fluoro-3-chlorobenzyl Alcohol; 1-(3-Chloro-2-fluorophenyl)methanol; 3-Chloro-2-fluoro-benzenemethanol; Benzenemethanol, 3-chloro-2-fluoro-; 3-Chloro-2-fluorophenylmethanol; 2-Fluoro-3-chlorophenylmethanol
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.