Description

2-Methyl-6-(Trifluoromethyl)Pyridine-3-Carbonyl Chloride is a high-value, reactive chemical intermediate characterized by its pyridine core and acid chloride functionality. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the introduction of the 2-methyl-6-(trifluoromethyl)pyridine moiety. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of small molecule drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging the biological activity of the trifluoromethylpyridine group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functional organic materials and liquid crystals due to its aromatic and electron-withdrawing properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies offering bespoke synthesis services.

Basic Information

Product Name	2-Methyl-6-(Trifluoromethyl)Pyridine-3-Carbonyl Chloride
CAS No.	261635-98-7
Molecular Formula	C8H5ClF3NO
Molecular Weight	223.58 g/mol
Synonyms	3-Pyridinecarbonyl chloride, 2-methyl-6-(trifluoromethyl)-; 2-Methyl-6-(trifluoromethyl)nicotinoyl chloride; 6-(Trifluoromethyl)-2-picolinoyl chloride; 2-Methyl-6-trifluoromethylpyridine-3-carbonyl chloride; 2-Methyl-6-(trifluoromethyl)pyridine-3-carboxylic acid chloride; 3-Carbamoyl-2-methyl-6-(trifluoromethyl)pyridine hydrochloride (precursor related); Nicotinoyl chloride, 2-methyl-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-(Trifluoromethyl)Pyridine-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from moisture, strong bases, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.