Description

Sodium 2-((2-Amino-6-Oxo-1H-Purin-9(6H)-Yl)Methoxy)Ethanolate Dihydrate is a high-purity, chemically defined salt form of a key nucleoside analog intermediate. This compound is critical for ensuring batch-to-batch consistency and optimal reactivity in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and nucleotide chemistry research.
• Prodrug Development: Employed in the design and synthesis of prodrugs to enhance the bioavailability and targeting of active pharmaceutical ingredients (APIs).
• Antiviral Agent Synthesis: A key precursor in the manufacturing chain for specific antiviral medications targeting viral polymerases.
• Labeled Compound Production: Acts as a starting material for the synthesis of isotopically labeled (e.g., 13C, 15N) compounds for use in pharmacokinetic and metabolic tracing studies.

Basic Information

Product Name	Sodium 2-((2-Amino-6-Oxo-1H-Purin-9(6H)-Yl)Methoxy)Ethanolate Dihydrate
CAS No.	261506-45-0
Molecular Formula	C8H11N5NaO4 • 2H2O
Molecular Weight	291.22 g/mol (Anhydrous basis)
Synonyms	9-[(2-Hydroxyethoxy)methyl]guanine Sodium Salt Dihydrate; Sodium Acyclovir Dihydrate; Acyclovir Sodium Salt Dihydrate; ACV Sodium Salt Dihydrate; Zovirax Impurity Sodium Salt; 2-((2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethanol Sodium Salt Dihydrate; NSC 757664 Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium 2-((2-Amino-6-Oxo-1H-Purin-9(6H)-Yl)Methoxy)Ethanolate Dihydrate is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided to ensure traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	10.0% - 13.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.