Description

Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(1Z)-1-Propenyl-, (1R,3S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its core value lies in its unique cyclopropane ring and propenyl side chain, which serve as key structural motifs for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS, antiviral, or anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide molecules, where the cyclopropane moiety can impart specific biological activity and stability.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Material Science Precursor: Potential building block for specialty polymers or liquid crystals where the rigid cyclopropane structure influences material properties.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of fine chemicals.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(1Z)-1-Propenyl-, (1R,3S)- (9Ci)
CAS No.	259670-71-8
Molecular Formula	C9H13ClO
Molecular Weight	172.65 g/mol
Synonyms	(1R,3S)-2,2-Dimethyl-3-[(1Z)-1-propen-1-yl]cyclopropanecarbonyl chloride; (1R-cis)-2,2-Dimethyl-3-(1Z)-1-propenylcyclopropanecarboxylic acid chloride; trans-(+)-Chrysanthemic acid chloride (cis/trans isomer); (1R,3S)-Chrysanthemoyl chloride (isomer); 2,2-Dimethyl-3-(1Z)-1-propenylcyclopropanecarbonyl chloride, (1R,3S)-; (1R,3S)-2,2-Dimethyl-3-(1-propenyl)cyclopropanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(1Z)-1-Propenyl-, (1R,3S)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity and isomeric composition, to support your critical R&D and scale-up activities. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its nature as a highly volatile and moisture-sensitive acid chloride, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (1R,3S)
Isomeric Purity (GC/HPLC)	≥ 95.0% (1Z)-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.