Description

Adenosine,8-Bromo-2-Deoxy-23-Fluoro-3",5-Bis-o-(Tetrahydro-2H is a high-purity, modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a critical building block in the synthesis of novel therapeutic agents, particularly in the fields of oncology and antiviral drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a specialized substrate or probe in enzymatic studies and metabolic pathway analysis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Pro-drug Synthesis: Acts as a core component in the design and synthesis of nucleotide pro-drugs for improved bioavailability.
• Labeled Compound Synthesis: A potential starting material for the synthesis of isotopically labeled compounds for pharmacokinetic and imaging studies.
• Academic Research: Utilized in university and institutional labs for fundamental research in nucleic acid chemistry and biology.

Basic Information

Product Name	Adenosine,8-Bromo-2-Deoxy-23-Fluoro-3",5-Bis-o-(Tetrahydro-2H
CAS No.	259144-92-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	8-Bromo-2'-deoxy-2'-fluoro-3',5'-bis-O-(tetrahydro-2H-pyran-2-yl)adenosine; 8-Br-2'-F-ara-A THP Protected; 8-Bromo-2'-deoxy-2'-fluoro-3',5'-di-O-(tetrahydropyran-2-yl)adenosine; 8-Bromo-2'-fluoro-2'-deoxy-3',5'-bis-O-(tetrahydro-2H-pyran-2-yl)adenosine; Modified Adenosine Derivative; THP-Protected Fluorinated Nucleoside
EINECS	Contact for details

Quality Control

Our Adenosine,8-Bromo-2-Deoxy-23-Fluoro-3",5-Bis-o-(Tetrahydro-2H is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.