Description

(S)-(E)-Luliconazole Isomer CAS NO 256424-63-2 is a specific stereoisomer of the potent antifungal agent Luliconazole, distinguished by its (S) and (E) stereochemistry. This high-purity isomer is critical for advanced pharmaceutical research and development, particularly in studying structure-activity relationships and developing novel antifungal formulations. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation antifungal therapies and analytical reference standards.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control of Luliconazole-based drug products.
• Antifungal Drug R&D: Used as a key intermediate or active pharmaceutical ingredient (API) in the research and development of new topical and systemic antifungal medications.
• Metabolite & Impurity Studies: Essential for the identification, synthesis, and toxicological profiling of stereospecific metabolites and process-related impurities.
• Biochemical Research: Employed in in-vitro and in-vivo studies to investigate the mechanism of action, potency, and selectivity of antifungal agents against various fungal strains.
• Formulation Development: Used in the development and stability testing of creams, ointments, and other dosage forms requiring a specific isomeric profile.

Basic Information

Product Name	(S)-(E)-Luliconazole Isomer
CAS No.	256424-63-2
Molecular Formula	C14H9Cl2N2S2
Molecular Weight	354.27 g/mol
Synonyms	(S,E)-Luliconazole; (-)-(S,E)-Luliconazole; (S,E)-N-(4-Chloro-2-(2,4-dichlorophenyl)thiazol-5-ylmethyl)-1-methyl-3-(2-propenyl)-2-imidazolidinone; (S,E)-N-[(4-Chloro-2-[(2,4-dichlorophenyl)thio]-5-thiazolyl]methyl]-1-methyl-3-(2-propenyl)-2-imidazolidinone; Luliconazole (S,E)-Isomer; Luliconazole Stereoisomer; Luliconazole Impurity
EINECS	Contact for details

Quality Control

Our (S)-(E)-Luliconazole Isomer is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high stereochemical purity and compliance with research-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S,E)-Isomer
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.