Description

(4-Chloro-2,5-Difluorophenyl)Methanol is a versatile fluorinated aromatic alcohol building block, essential for advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine substituents enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Acts as a monomer or intermediate in the production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The benzylic alcohol group can be activated for use in Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Protecting Group Chemistry: Can be used to introduce protecting groups or as a masked aldehyde/carboxylic acid precursor in multi-step syntheses.

Basic Information

Product Name	(4-Chloro-2,5-Difluorophenyl)Methanol
CAS No.	252004-49-2
Molecular Formula	C7H5ClF2O
Molecular Weight	178.56 g/mol
Synonyms	(4-Chloro-2,5-difluorophenyl)methanol; 4-Chloro-2,5-difluorobenzyl alcohol; 2,5-Difluoro-4-chlorobenzyl alcohol; 1-(Chloro-2,5-difluoro-4-phenyl)methanol; Benzenemethanol, 4-chloro-2,5-difluoro-; (4-Chloro-2,5-difluorophenyl)carbinol
EINECS	Contact for details

Quality Control

Our (4-Chloro-2,5-Difluorophenyl)Methanol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.