Description

1-(2-Chlorophenyl)-2,2,2-Trifluoroethanol is a versatile fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a chlorophenyl ring and a trifluoroethanol moiety, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated components for liquid crystal displays (LCDs), influencing dielectric anisotropy and viscosity.
• Advanced Material Science: Employed in the synthesis of specialty polymers and coatings, where the phenyl and fluorine groups contribute to unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Acts as a chiral precursor or a protecting group in sophisticated multi-step synthetic routes for fine chemicals and complex natural product analogs.

Basic Information

Product Name	1-(2-Chlorophenyl)-2,2,2-Trifluoroethanol
CAS No.	251352-64-4
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	2-Chloro-α-(trifluoromethyl)benzyl Alcohol; (2-Chlorophenyl)(trifluoromethyl)methanol; α-(Trifluoromethyl)-2-chlorobenzenemethanol; 1-(2-Chlorophenyl)-2,2,2-trifluoroethan-1-ol; 2-Chloro-α,α,α-trifluorotoluene; o-Chloro-α-(trifluoromethyl)benzyl Alcohol; 2-Chlorobenzotrifluoride alcohol
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)-2,2,2-Trifluoroethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.