Description

Otophylloside F is a bioactive triterpenoid saponin isolated from plant sources such as Otophora spp. and related medicinal herbs, valued for its structural complexity and pharmacological potential. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in natural product research and phytochemical development. Researchers and contract development organizations (CDOs) in academic, biotech, and pharmaceutical sectors rely on high-purity Otophylloside F CAS NO 250217-73-3 for mechanistic studies, assay validation, and preclinical candidate screening.

Application

• Reference standard for HPLC and LC-MS quantitative analysis of saponin-rich botanical extracts
• Lead compound in anti-inflammatory and immunomodulatory drug discovery programs
• Active ingredient in preclinical studies evaluating hepatoprotective and neuroprotective effects
• Tool compound for structure–activity relationship (SAR) studies of oleanane-type saponins
• Quality control marker for standardization of traditional herbal formulations containing Otophora or Phyllanthus species
• Substrate in enzymatic glycosylation and biotransformation research

Basic Information

Product Name	Otophylloside F
CAS No.	250217-73-3
Molecular Formula	C42H68O14
Molecular Weight	797.00 g/mol
Synonyms	Otophylloside F; Otophylloside-F; 3-O-[β-D-Glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl]-23-hydroxyolean-12-en-28-oic acid; 23-Hydroxyolean-12-en-28-oic acid 3-O-{[β-D-glucopyranosyl-(1→3)]-[β-D-glucopyranosyl-(1→3)]-α-L-rhamnopyranoside}; NSC 727507; CID 11347585; UNII-7QZ3V8XJ1F
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are verified for identity (IR, NMR, MS), assay (HPLC), and impurity profile (residual solvents, heavy metals, microbial limits) per ICH Q3 guidelines. The material meets requirements for research-grade and analytical reference use, with optional certification to ISO 9001 and GMP-compliant manufacturing documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8°C under inert atmosphere (nitrogen or argon) to prevent oxidation and degradation. Due to hygroscopic nature, maintain low-humidity conditions (<30% RH) and minimize exposure to ambient air during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances	≤ 2.0% total impurities
Residual Solvents	Meets ICH Q3C limits
Water Content (Karl Fischer)	≤ 5.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.