Description

6H-Purin-6-One, 2-Amino-9-(2S,3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)-2-Pyrrolidinylmethyl-1,9-Dihydro- is a high-purity nucleoside analogue with significant potential in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of next-generation nucleotide-based drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleotide analogues.
• Antiviral Drug Research: Investigated for its potential as a precursor or active moiety in drugs targeting viral polymerases.
• Oncology Research: Used in the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid biochemistry.
• Preclinical Development: Utilized in formulation studies, pharmacokinetic profiling, and toxicology assessments for new drug candidates.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	6H-Purin-6-One, 2-Amino-9-(2S,3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)-2-Pyrrolidinylmethyl-1,9-Dihydro-
CAS No.	249503-30-8
Molecular Formula	C11H16N6O4
Molecular Weight	296.28 g/mol
Synonyms	2-Amino-9-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,9-dihydro-6H-purin-6-one; 2-Amino-9-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; 2-Aminopurine nucleoside derivative; (2S,3S,4R,5R)-2-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
EINECS	Contact for details

Quality Control

Our 6H-Purin-6-One, 2-Amino-9-(2S,3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)-2-Pyrrolidinylmethyl-1,9-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification and impurity profiling. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full transparency and compliance with your research or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.