Description

Erlotinib Mesylate is the mesylate salt form of erlotinib, a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of targeted cancer therapies. It is essential for pharmaceutical manufacturers and research institutions developing treatments for non-small cell lung cancer (NSCLC) and pancreatic cancer.

Application

• Primary Active Pharmaceutical Ingredient (API) in the manufacture of targeted oncology drugs.
• Key intermediate in advanced pharmaceutical research and development for EGFR-mutated cancers.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Biochemical research tool for studying EGFR signaling pathways and mechanisms of drug resistance.
• Starting material for the synthesis of novel drug derivatives and prodrugs.
• Used in preclinical and clinical studies to evaluate efficacy and pharmacokinetics.

Basic Information

Item	Details
Product Name	Erlotinib Mesylate
CAS No.	248594-19-6
Molecular Formula	C22H23N3O4 · CH4O3S
Molecular Weight	429.5 g/mol (Free base: 393.4 g/mol)
Synonyms	Erlotinib Methanesulfonate; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Methanesulfonate; OSI-774 Mesylate; Tarceva Mesylate; CP-358774 Mesylate; NSC 718781; 6,7-Bis(2-methoxyethoxy)quinazolin-4-yl-(3-ethynylphenyl)amine methanesulfonate
EINECS	Contact for details

Quality Control

Our Erlotinib Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥98.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.5%; Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.