Description

5-Methyl-2-Thioxylouridine is a modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical building block and a key intermediate in the synthesis of novel therapeutic agents and diagnostic probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, anticancer therapies, and molecular biology tools. The product's unique thio-substituted structure offers distinct chemical properties for probing biological mechanisms and designing targeted treatments.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand metabolic pathways and nucleic acid biochemistry.
• Proteomics & Genomics: Acts as a modified building block for oligonucleotide synthesis, enabling the study of RNA structure, function, and protein-RNA interactions.
• Diagnostic Development: Potential use in the creation of labeled probes for diagnostic assays and imaging techniques.
• Antiviral Drug Discovery: Investigated for its activity and mechanism against various viral targets due to its nucleoside analog structure.
• Academic Research: Employed in university and institutional labs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	5-Methyl-2-Thioxylouridine
CAS No.	246857-26-1
Molecular Formula	C10H14N2O5S
Molecular Weight	274.29 g/mol
Synonyms	5-Methyl-2-thiouridine; 2-Thio-5-methyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-1,2-dihydropyrimidin-4-one; 5-Methyl-2-thioxo-1-((2R,3R,4S,5R)-3,4,5-trihydroxytetrahydrofuran-2-yl)pyrimidin-4(1H)-one; 2-Thio-5-methyl-1-β-D-ribofuranosyluracil
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Thioxylouridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.