Description

3-Furancarbonyl Chloride, 4-(Chloromethyl)-2,5-Dimethyl- (9Ci) is a highly reactive, multi-functional heterocyclic building block. This compound is valued for its dual functionality, featuring both an acid chloride and a chloromethyl group, which enables its use in sequential or convergent synthetic pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel furan-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the furan ring system imparts specific biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and natural product analogs via nucleophilic substitution and acylation reactions.
• Ligand and Catalyst Development: Useful for synthesizing novel chelating ligands or organocatalysts containing the furan scaffold.

Basic Information

Item	Details
Product Name	3-Furancarbonyl Chloride, 4-(Chloromethyl)-2,5-Dimethyl- (9Ci)
CAS No.	246178-78-9
Molecular Formula	C8H8Cl2O2
Molecular Weight	207.05 g/mol
Synonyms	4-(Chloromethyl)-2,5-dimethylfuran-3-carbonyl chloride; 2,5-Dimethyl-4-(chloromethyl)furan-3-carbonyl chloride; 3-Furoyl chloride, 4-(chloromethyl)-2,5-dimethyl-; 4-(Chloromethyl)-2,5-dimethyl-3-furancarboxylic acid chloride; 246178-78-9; 4-Chloromethyl-2,5-dimethyl-3-furoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Furancarbonyl Chloride, 4-(Chloromethyl)-2,5-Dimethyl- (9Ci) is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO-guided applications, ensuring traceability and compliance for advanced R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.