Description

3-Cyclopentene-1,3-Dicarbonyl Difluoride, 1,2,2-Trimethyl-, (1R)- (9Ci) is a high-purity, chiral fluorinated building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, which incorporates both a reactive dicarbonyl difluoride moiety and a defined stereocenter, enabling the precise construction of complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance metabolic stability and biological activity.
• Fluorination Reagent: Serves as a versatile reagent for introducing fluorinated carbonyl groups into target molecules under controlled conditions.
• Asymmetric Synthesis: Exploited in stereoselective reactions to create enantiomerically pure compounds for high-value applications.
• Material Science Precursor: Potential use in the synthesis of specialized fluorinated polymers or coatings with unique properties.
• Academic & Contract Research: A valuable tool for methodological development in organic chemistry and for custom synthesis projects in CRO (Contract Research Organization) settings.

Basic Information

Product Name	3-Cyclopentene-1,3-Dicarbonyl Difluoride, 1,2,2-Trimethyl-, (1R)- (9Ci)
CAS No.	245655-52-1
Molecular Formula	C10H12F2O2
Molecular Weight	202.20 g/mol
Synonyms	(1R)-1,2,2-Trimethyl-3-cyclopentene-1,3-dicarbonyl difluoride; (R)-1,2,2-Trimethyl-3-cyclopentene-1,3-dicarbonyl difluoride; 3-Cyclopentene-1,3-dicarbonyl difluoride, 1,2,2-trimethyl-, (1R)-; (1R)-1,2,2-Trimethylcyclopent-3-ene-1,3-dicarbonyl difluoride; Fluorinated chiral cyclopentene derivative; CAS 245655-52-1
EINECS	Contact for details

Quality Control

Our 3-Cyclopentene-1,3-Dicarbonyl Difluoride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee reproducible results in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong alkalis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.