Description

Thymidine 5'-(Trihydrogen Diphosphate) P'-(4-Amino-4,6-Dideoxy-α-D-Glucopyranosyl) Ester is a specialized nucleotide-sugar conjugate, a key biochemical building block in the study and synthesis of complex biomolecules. This compound is critical for researchers and manufacturers requiring high-purity intermediates for advanced life science applications. It is primarily utilized in pharmaceutical research, enzymatic studies, and the development of novel nucleotide-based therapeutics, where precise molecular structure and purity are paramount.

Application

• Enzymatic Substrate: Used as a specific substrate in biochemical assays to study glycosyltransferase and related enzyme activities.
• Nucleotide Synthesis: Serves as a crucial activated sugar donor intermediate in the chemical and enzymatic synthesis of modified nucleotides and oligonucleotides.
• Antibiotic Research: Acts as a biochemical tool in the investigation of biosynthetic pathways for aminoglycoside and nucleoside antibiotics.
• Glycobiology Studies: Employed in research focused on carbohydrate metabolism and the synthesis of complex glycoconjugates.
• Pharmaceutical Intermediate: A potential high-value building block for the research and development of targeted antiviral or anticancer prodrugs.
• Metabolic Pathway Analysis: Used as a tracer or standard in mass spectrometry-based studies of nucleotide-sugar metabolism.

Basic Information

Product Name	Thymidine 5'-(Trihydrogen Diphosphate) P'-(4-Amino-4,6-Dideoxy-α-D-Glucopyranosyl) Ester
CAS No.	244226-72-0
Molecular Formula	C16H27N4O14P2
Molecular Weight	585.35 g/mol
Synonyms	dTDP-4-Amino-4,6-dideoxy-α-D-glucose; dTDP-4-Amino-4,6-dideoxy-D-glucose; Thymidine 5'-(trihydrogen diphosphate) P'-(4-amino-4,6-dideoxy-α-D-glucopyranosyl) ester; TDP-4-Amino-4,6-dideoxyglucose; 4-Amino-4,6-dideoxy-α-D-glucose thymidylyltransferase substrate; dTDP-Quinovosamine; Nucleotide-sugar conjugate CAS 244226-72-0
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stability. A comprehensive Certificate of Analysis (COA) detailing assay purity, impurity profile, and specific tests is provided with every shipment to ensure it meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.