Description

7-Chlorobenzo[B]Thiophene-2-Carbonyl Chloride is a high-purity, reactive organic intermediate featuring both a chlorinated benzothiophene core and an acid chloride functional group. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a versatile building block. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, including kinase inhibitors and other heterocyclic-based therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the benzothiophene scaffold for biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials and specialty polymers.
• Chemical Biology Probes: Employed in the creation of tagged molecules and activity-based probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	7-Chlorobenzo[B]Thiophene-2-Carbonyl Chloride
CAS No.	244126-68-9
Molecular Formula	C9H4Cl2OS
Molecular Weight	231.10 g/mol
Synonyms	7-Chlorobenzo[b]thiophene-2-carbonyl chloride; 2-Chlorocarbonyl-7-chlorobenzo[b]thiophene; 7-Chloro-1-benzothiophene-2-carbonyl chloride; 7-Chlorobenzo[b]thien-2-yl carbonyl chloride; 7-Chloro-benzo[b]thiophene-2-carboxylic acid chloride; 244126-68-9; 7-Chloro-1-benzothiophene-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 7-Chlorobenzo[B]Thiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.