Description

2,4-Dibromo-6-Fluorophenyl Isothiocyanate is a specialized halogenated aromatic isothiocyanate building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines bromine, fluorine, and a highly reactive isothiocyanate group, enabling precise derivatization and the construction of complex heterocyclic systems. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor for synthesizing novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and pesticides with enhanced activity profiles.
• Ligand and Probe Synthesis: Employed to create specialized chemical probes, fluorescent tags, or chelating ligands for biochemical and diagnostic applications.
• Heterocyclic Chemistry: Serves as a versatile starting material for constructing complex sulfur- and nitrogen-containing heterocycles like benzothiazoles and thioureas.
• Material Science: Potential monomer or cross-linking agent in the development of advanced polymers with specific electronic or thermal properties.
• Chemical Biology: Useful for bioconjugation and protein labeling studies due to the reactivity of the isothiocyanate group with amines.

Basic Information

Product Name	2,4-Dibromo-6-Fluorophenyl Isothiocyanate
CAS No.	244022-67-1
Molecular Formula	C7H2Br2FNS
Molecular Weight	327.97 g/mol
Synonyms	2,4-Dibromo-6-fluorophenyl isothiocyanate; 1,3-Dibromo-5-fluorophenyl isothiocyanate; 6-Fluoro-2,4-dibromophenyl isothiocyanate; Isothiocyanic acid, 2,4-dibromo-6-fluorophenyl ester; 2,4-Dibromo-6-fluoro-1-isothiocyanatobenzene; (2,4-Dibromo-6-fluorophenyl) isothiocyanate
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-6-Fluorophenyl Isothiocyanate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.