Description

1H-Pyrazole-4-Carbonyl Chloride, 3-Chloro-1-Cyclopropyl- (9Ci) is a high-value, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because its unique pyrazole-carbonyl chloride structure enables the efficient introduction of functionalized heterocyclic motifs into target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly in the development of new therapeutic agents and crop protection chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other enzyme modulators.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial labs for exploring new reaction pathways and creating complex molecular architectures.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands for catalytic systems, where the pyrazole moiety can impart specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1H-Pyrazole-4-Carbonyl Chloride, 3-Chloro-1-Cyclopropyl- (9Ci)
CAS No.	243120-24-3
Molecular Formula	C7H6Cl2N2O
Molecular Weight	205.04 g/mol
Synonyms	3-Chloro-1-cyclopropyl-1H-pyrazole-4-carbonyl chloride; 1-Cyclopropyl-3-chloro-1H-pyrazole-4-carbonyl chloride; 3-Chloro-1-cyclopropylpyrazole-4-carbonyl chloride; 1H-Pyrazole-4-carbonyl chloride, 3-chloro-1-cyclopropyl-; 243120-24-3; 3-Chloro-1-cyclopropyl-1H-pyrazole-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-4-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with cGMP and ISO 9001 standards for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.