Description

Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(1Z)-1-Propenyl-, (1R,3R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in the unique, strained cyclopropane ring and the reactive acid chloride functional group, which enable precise molecular construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane moiety can impart specific biological activity and stability.
• Asymmetric Catalysis Research: Serves as a sophisticated substrate or ligand precursor in the development of new catalytic methodologies for stereoselective bond formation.
• Material Science Precursor: Employed in the synthesis of specialized monomers or cross-linking agents for advanced polymeric materials with tailored properties.
• Chemical Biology Probe Development: Utilized to create activity-based probes or labeled compounds for studying enzyme function and biological pathways.

Basic Information

Item	Details
Product Name	Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(1Z)-1-Propenyl-, (1R,3R)- (9Ci)
CAS No.	240494-65-9
Molecular Formula	C9H13ClO
Molecular Weight	172.65 g/mol
Synonyms	(1R,3R)-2,2-Dimethyl-3-[(1Z)-1-propen-1-yl]cyclopropanecarbonyl Chloride; (1R,3R)-Chrysanthemoyl Chloride (cis-isomer); (1R,3R)-2,2-Dimethyl-3-(1Z)-propenylcyclopropanecarboxylic Acid Chloride; (1R-cis)-2,2-Dimethyl-3-(1Z)-1-propenylcyclopropanecarbonyl Chloride; trans-(Z)-Chrysanthemoyl Chloride (specific isomer); (1R,3R)-trans-Chrysanthemic Acid Chloride (Z-isomer); Pyrethroid Acid Chloride Intermediate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(1Z)-1-Propenyl-, (1R,3R)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC analysis, to confirm identity, isomeric purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its moisture-sensitive and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% (1R,3R)-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.