Description

D-Threo-Penturonic Acid, 2-(Acetylamino)-2,3-Dideoxy-, γ-Lactone, 5-Methyl Ester (9Ci) CAS NO 239125-39-4 is a specialized, high-purity chemical building block characterized by its unique penturonic acid backbone with an acetylated amino group and a γ-lactone ring. This compound is of significant value in advanced organic synthesis and pharmaceutical research, serving as a critical chiral intermediate for the development of novel therapeutic agents and complex carbohydrate analogs. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing nucleoside analogs, antiviral compounds, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel nucleoside-based antiviral and anticancer drugs.
• Carbohydrate Chemistry Research: Used as a sophisticated building block for synthesizing complex, non-natural sugars and glycomimetics.
• Process Chemistry & Scale-up: Serves as a starting material or advanced intermediate in the optimization and production of active pharmaceutical ingredients (APIs).
• Biochemical Tool Development: Potential use in creating enzyme inhibitors or probes for studying glycosidase and glycosyltransferase enzymes.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of high-value, specialty chemicals for agrochemical and material science applications.
• Academic & Institutional Research: A valuable compound for universities and research institutes exploring new synthetic methodologies and bioorganic chemistry.

Basic Information

Product Name	D-Threo-Penturonic Acid, 2-(Acetylamino)-2,3-Dideoxy-, γ-Lactone, 5-Methyl Ester (9Ci)
CAS No.	239125-39-4
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	2-Acetamido-2,3-dideoxy-D-threo-penturonic acid γ-lactone 5-methyl ester; Methyl 2-acetamido-2,3-dideoxy-D-threo-pent-2-enofuranosid-4-uronate; 5-Methyl 2-(acetylamino)-2,3-dideoxy-D-threo-pent-2-enofuranosid-4-uronate; D-threo-Pent-2-enofuranosid-4-uronic acid, 2-(acetylamino)-2,3-dideoxy-, γ-lactone, 5-methyl ester; 239125-39-4; (2R,4S,5R)-5-Methyl 2-acetamido-2,3-dideoxypent-2-enofuranosid-4-uronate
EINECS	Contact for details

Quality Control

Our D-Threo-Penturonic Acid, 2-(Acetylamino)-2,3-Dideoxy-, γ-Lactone, 5-Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS) to ensure structural integrity and batch-to-batch consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming specifications for identity, purity, and impurities. Our quality system supports development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.