Description

4-Bromo-2-(trifluoromethoxy)phenyl isothiocyanate is a specialized aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromo and trifluoromethoxy substituents, makes it a valuable precursor for constructing complex heterocycles and functional materials. This high-purity intermediate is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Agrochemical Research: Building block for developing new generation pesticides and herbicides with enhanced activity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for creating advanced polymers and functional materials with specific electronic or surface properties.
• Chemical Biology Probes: Useful for synthesizing activity-based probes (ABPs) for enzyme profiling and target identification.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Item	Details
Product Name	4-Bromo-2-(trifluoromethoxy)phenyl isothiocyanate
CAS No.	238742-91-1
Molecular Formula	C8H3BrF3NOS
Molecular Weight	298.08 g/mol
Synonyms	1-Bromo-4-isothiocyanato-2-(trifluoromethoxy)benzene; 4-Bromo-2-(trifluoromethoxy)benzenisothiocyanate; 2-(Trifluoromethoxy)-4-bromophenyl isothiocyanate; 4-Bromo-α,α,α-trifluoro-o-anisyl isothiocyanate; [4-Bromo-2-(trifluoromethoxy)phenyl] isothiocyanate; 4-Bromo-2-trifluoromethoxyphenyl isothiocyanate
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(trifluoromethoxy)phenyl isothiocyanate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.