Description

n-Ethyl-4-Fluoro-3-Nitrobenzamide is a specialized fluorinated nitrobenzamide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine substituent and a nitro group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Synthesis: Serves as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aromatic systems.
• Dye & Pigment Intermediate: Employed in the production of advanced colorants and fluorophores for analytical and imaging applications.

Basic Information

Product Name	n-Ethyl-4-Fluoro-3-Nitrobenzamide
CAS No.	235428-18-9
Molecular Formula	C9H9FN2O3
Molecular Weight	212.18 g/mol
Synonyms	4-Fluoro-3-nitro-N-ethylbenzamide; N-Ethyl-4-fluoro-3-nitrobenzamide; Benzamide, N-ethyl-4-fluoro-3-nitro-; 235428-18-9; 4-Fluoro-3-nitrobenzoic acid ethylamide; Ethyl (4-fluoro-3-nitrobenzoyl)amine; 3-Nitro-4-fluoro-N-ethylbenzamide
EINECS	Contact for details

Quality Control

Our n-Ethyl-4-Fluoro-3-Nitrobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.