Description

Micafungin is a potent semisynthetic echinocandin antifungal agent derived from the fungus Coleophoma empetri. This compound is critically important for its targeted mechanism of action, inhibiting the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall. It is primarily utilized in the pharmaceutical industry for the development of sterile injectable formulations to treat serious systemic fungal infections, including invasive candidiasis and aspergillosis, in hospital and clinical settings.

Application

• Active Pharmaceutical Ingredient (API): Core component in the manufacture of sterile antifungal injectable drugs.
• Hospital-Acquired Infection Treatment: Used in formulations targeting invasive candidiasis, candidemia, and esophageal candidiasis in immunocompromised patients.
• Prophylactic Antifungal Therapy: Employed in drug products for preventing fungal infections in patients undergoing hematopoietic stem cell transplantation.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological studies and the development of new antifungal agents.
• Veterinary Pharmaceuticals: Investigated for use in antifungal treatments for serious fungal infections in animals.

Basic Information

Product Name	Micafungin
CAS No.	235114-32-6
Molecular Formula	C56H71N9O23S
Molecular Weight	1270.28 g/mol
Synonyms	Micafungin Sodium; FK-463; Mycamine; FR-901379; (4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-3-hydroxy-L-ornithyl-trans-4-hydroxy-L-prolyl-(R)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-3-[(1E)-1,3-dihydroxy-3-(sulfooxy)-1-propen-1-yl]-L-tyrosinamide; Echinocandin B derivative
EINECS	Contact for details

Quality Control

Our Micafungin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are provided, detailing specifications for identity, purity, potency, and related substances. We support compliance with cGMP (current Good Manufacturing Practice), ICH guidelines, and relevant pharmacopoeial standards (USP/EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept under conditions that prevent exposure to excessive humidity. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.25 EU/mg
Microbial Enumeration	Conforms to USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.