Description

2-Pyridinecarbonyl Chloride, 4-Nitro- (9Ci) is a versatile and highly reactive chemical building block, primarily used as an intermediate in advanced organic synthesis. Its value lies in its ability to introduce the 4-nitropyridine-2-carbonyl moiety, a key functional group for constructing complex molecules with specific electronic and binding properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the nitropyridine structure confers specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and R&D: A critical reagent for contract research organizations (CROs) and academic laboratories engaged in novel heterocyclic chemistry.

Basic Information

Product Name	2-Pyridinecarbonyl Chloride, 4-Nitro- (9Ci)
CAS No.	230312-97-7
Molecular Formula	C6H3ClN2O3
Molecular Weight	186.55 g/mol
Synonyms	4-Nitropicolinoyl Chloride; 4-Nitro-2-pyridinecarbonyl chloride; 4-Nitropyridine-2-carbonyl chloride; 2-Pyridinecarbonyl chloride, 4-nitro-; 4-Nitro-2-picolinoyl chloride; Picolinoyl chloride, 4-nitro-; 4-Nitropicolinic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridinecarbonyl Chloride, 4-Nitro- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. For long-term storage, temperatures of 2-8°C are recommended. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.