Description

(2E)-3-(2,6-Dichlorophenyl)Acryloyl Chloride is a high-purity, reactive organic intermediate characterized by its acryloyl chloride functional group and dichlorinated aromatic ring. This compound is a critical building block in advanced organic synthesis, enabling the efficient introduction of the (2E)-3-(2,6-dichlorophenyl)acryloyl moiety into target molecules. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the production of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the dichlorophenyl group.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the creation of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(2E)-3-(2,6-Dichlorophenyl)Acryloyl Chloride
CAS No.	230305-41-6
Molecular Formula	C9H5Cl3O
Molecular Weight	235.49 g/mol
Synonyms	(E)-3-(2,6-Dichlorophenyl)acryloyl chloride; trans-3-(2,6-Dichlorophenyl)acryloyl chloride; 2,6-Dichlorocinnamoyl chloride; (2E)-3-(2,6-Dichlorophenyl)-2-propenoyl chloride; 230305-41-6; (E)-2,6-Dichlorocinnamoyl chloride; 3-(2,6-Dichlorophenyl)prop-2-enoyl chloride
EINECS	Contact for details

Quality Control

Every batch of (2E)-3-(2,6-Dichlorophenyl)Acryloyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results for purity (HPLC), identity (IR, NMR), and specific impurity profiles, is supplied with each shipment to guarantee reproducible performance and supply chain traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept sealed to exclude moisture and stored separately from bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.