Description

3-Butyn-2-Ol,4-(4-Fluorophenyl)-(9Ci) CAS NO 229015-32-1 is a specialized fluorinated alkyne derivative, serving as a crucial chiral building block and advanced pharmaceutical intermediate. Its unique structure, featuring both an alkyne and a fluorinated aromatic ring, makes it a high-value synthon for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and materials science.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand & Catalyst Synthesis: Serves as a building block for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the research of advanced polymers and functional materials, where its alkyne group allows for click chemistry modifications.
• Chemical Biology & Proteomics: Acts as a probe or tagging agent due to its reactive alkyne handle for bioorthogonal conjugation strategies.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and fluorine chemistry.

Basic Information

Product Name	3-Butyn-2-Ol,4-(4-Fluorophenyl)-(9Ci)
CAS No.	229015-32-1
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	4-(4-Fluorophenyl)-3-butyn-2-ol; 4-(4-Fluorophenyl)but-3-yn-2-ol; 1-(4-Fluorophenyl)-3-butyn-2-ol; (RS)-4-(4-Fluorophenyl)but-3-yn-2-ol; (±)-4-(4-Fluorophenyl)-3-butyn-2-ol; 3-Butyn-2-ol, 4-(4-fluorophenyl)-; 229015-32-1; 4-(p-Fluorophenyl)-3-butyn-2-ol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemicals. Each batch of 3-Butyn-2-Ol,4-(4-Fluorophenyl)-(9Ci) is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (by HPLC or GC), chiral purity (if applicable), and impurity profiles. Our quality system supports cGMP compliance for pharmaceutical applications, and we can accommodate custom purity requirements for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid or clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Standard Grade), ≥98.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.